2025 College Football Odds and Opening Lines for Week 0, Week 1

  • Bovada Sportsbook released opening lines for the 2025 college football season.
  • Week 0 odds favor the Kansas State Wildcats (-2.5) over the Iowa State Cyclones in Dublin, Ireland.
  • Some Week 1 featured games include Alabama as 9.5-point favorites against Florida State and Tennessee as a 14.5-point favorite against Syracuse in their matchup at Mercedes-Benz Stadium in Atlanta, Georgia.

DUBLINOpening lines for Week 0 and Week 1 of the 2025 college football season are available at Bovada Sportsbook. The Kansas State Wildcats are 2.5-point favorites against the Iowa State Cyclones in their Week 0 headliner in Dublin, Ireland.

Iowa State vs Kansas State Week 0 Odds

Team Spread
Iowa State +2.5 (-110)
Kansas State -2.5 (-110)

There aren’t any college football props available just yet for the season opener, but bettors can get in on the action with a spread bet despite the game being six months away. There are -110 odds for either side to cover the spread at Aviva Stadium.

Week 1 College Football Opening Lines At Bovada Sportsbook

As for Week 1, there are two games that stand out as intriguing matchups. The Florida State Seminoles look to bounce back from a rough 2024 season but are 9.5-point home underdogs against the Alabama Crimson Tide in their season opener.

Alabama vs Florida State Week 1 Odds

Team Spread
Alabama -9.5 (-110)
Florida State +9.5 (-110)

Redshirt junior and former five-star recruit Ty Simpson expects to be the starting quarterback for Alabama following the departure of Jalen Milroe. Florida State will also have a new starting quarterback with Boston College transfer Thomas Castellanos.

Tennessee vs Syracuse Week 1 Odds

Team Spread
Tennessee -14.5 (-115)
Syracuse +14.5 (-105)

The Tennessee Volunteers start their 2025-2026 campaign as 14.5-point favorites over the Syracuse Orange in Atlanta, Georgia. Bovada is one of the few college football prop sites with opening betting odds for seven other Week 0/Week 1 games.

About Zachary Kelley

Zach graduated with an Editing, Writing, and Media degree from Florida State University. He enjoys writing news stories about trending sporting events and sports betting legalization. His favorite college football props to bet on are team totals and quarterback rushing yards props.